Food Effects on Oral Drug Absorption: Application of Physiologically-Based Pharmacokinetic Modeling as a Predictive Tool

The bioavailability of an orally administered small molecule is often dictated by drug-specific physicochemical characteristics and is influenced by many biological processes. For example, in fed or fasted conditions, the transit time within the gastrointestinal tract can vary, confounding the abili...

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Detalles Bibliográficos
Autores principales: Cheng, Lisa, Wong, Harvey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408216/
https://www.ncbi.nlm.nih.gov/pubmed/32708881
http://dx.doi.org/10.3390/pharmaceutics12070672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408216/
https://www.ncbi.nlm.nih.gov/pubmed/32708881
http://dx.doi.org/10.3390/pharmaceutics12070672

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