Dual Targeting of VEGFR2 and C-Met Kinases via the Design and Synthesis of Substituted 3-(Triazolo-thiadiazin-3-yl)indolin-2-one Derivatives as Angiogenesis Inhibitors

[Image: see text] The vascular endothelial growth factor receptor 2 (VEGFR2) and c-mesenchymal epithelial transition factor (c-Met) are members of receptor tyrosine kinases which have a crucial role in the process of angiogenesis. Isatin moiety is a versatile group that is shared in many compounds t...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohamady, Samy, Galal, Mahmoud, Eldehna, Wagdy M., Gutierrez, David C., Ibrahim, Hany S., Elmazar, Mohey M., Ali, Hamed I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408256/
https://www.ncbi.nlm.nih.gov/pubmed/32775889
http://dx.doi.org/10.1021/acsomega.0c02038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408256/
https://www.ncbi.nlm.nih.gov/pubmed/32775889
http://dx.doi.org/10.1021/acsomega.0c02038

Ejemplares similares