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Dual Targeting of VEGFR2 and C-Met Kinases via the Design and Synthesis of Substituted 3-(Triazolo-thiadiazin-3-yl)indolin-2-one Derivatives as Angiogenesis Inhibitors
[Image: see text] The vascular endothelial growth factor receptor 2 (VEGFR2) and c-mesenchymal epithelial transition factor (c-Met) are members of receptor tyrosine kinases which have a crucial role in the process of angiogenesis. Isatin moiety is a versatile group that is shared in many compounds t...
Autores principales: | Mohamady, Samy, Galal, Mahmoud, Eldehna, Wagdy M., Gutierrez, David C., Ibrahim, Hany S., Elmazar, Mohey M., Ali, Hamed I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408256/ https://www.ncbi.nlm.nih.gov/pubmed/32775889 http://dx.doi.org/10.1021/acsomega.0c02038 |
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