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Targeting Altered Energy Metabolism in Colorectal Cancer: Oncogenic Reprogramming, the Central Role of the TCA Cycle and Therapeutic Opportunities

Colorectal cancer (CRC) is among the most frequent cancer entities worldwide. Multiple factors are causally associated with CRC development, such as genetic and epigenetic alterations, inflammatory bowel disease, lifestyle and dietary factors. During malignant transformation, the cellular energy met...

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Detalles Bibliográficos
Autores principales: Neitzel, Carina, Demuth, Philipp, Wittmann, Simon, Fahrer, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408264/
https://www.ncbi.nlm.nih.gov/pubmed/32610612
http://dx.doi.org/10.3390/cancers12071731