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Salt Cocrystal of Diclofenac Sodium-L-Proline: Structural, Pseudopolymorphism, and Pharmaceutics Performance Study

Previously, we have reported on a zwitterionic cocrystal of diclofenac acid and L-proline. However, the solubility of this multicomponent crystal was still lower than that of diclofenac sodium salt. Therefore, this study aimed to observe whether a multicomponent crystal could be produced from diclof...

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Detalles Bibliográficos
Autores principales: Nugrahani, Ilma, Kumalasari, Rizka A., Auli, Winni N., Horikawa, Ayano, Uekusa, Hidehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408265/
https://www.ncbi.nlm.nih.gov/pubmed/32708314
http://dx.doi.org/10.3390/pharmaceutics12070690