Combinatorial Inhibition of Cell Surface Receptors Using Dual Aptamer-Functionalized Nanoconstructs for Cancer Treatment

Membrane receptors overexpressed in diseased states are considered novel therapeutic targets. However, the single targeting approach faces several fundamental issues, such as poor efficacy, resistance, and toxicity. Here, we report a dual-targeting strategy to enhance anti-cancer efficacy via synerg...

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Detalles Bibliográficos
Autores principales: Lee, Hyojin, Kim, Tae Hee, Park, Daechan, Jang, Mihue, Chung, Justin J., Kim, Soo Hyun, Kim, Sang-Heon, Lee, Kwan Hyi, Jung, Youngmee, Oh, Seung Ja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408393/
https://www.ncbi.nlm.nih.gov/pubmed/32708267
http://dx.doi.org/10.3390/pharmaceutics12070689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408393/
https://www.ncbi.nlm.nih.gov/pubmed/32708267
http://dx.doi.org/10.3390/pharmaceutics12070689

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