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Methylation in HOX Clusters and Its Applications in Cancer Therapy

HOX genes are commonly known for their role in embryonic development, defining the positional identity of most structures along the anterior–posterior axis. In postembryonic life, HOX gene aberrant expression can affect several processes involved in tumorigenesis such as proliferation, apoptosis, mi...

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Detalles Bibliográficos
Autores principales: Paço, Ana, de Bessa Garcia, Simone Aparecida, Freitas, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408435/
https://www.ncbi.nlm.nih.gov/pubmed/32635388
http://dx.doi.org/10.3390/cells9071613