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High Content Imaging of Barrett’s-Associated High-Grade Dysplasia Cells After siRNA Library Screening Reveals Acid-Responsive Regulators of Cellular Transitions

BACKGROUND & AIMS: Esophageal adenocarcinoma (EAC) develops from within Barrett’s esophagus (BE) concomitant with gastroesophageal reflux disease (GERD). Wound healing processes and cellular transitions, such as epithelial–mesenchymal transitions, may contribute to the development of BE and the...

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Detalles Bibliográficos
Autores principales: Phipps, Sinead M., Garry, Catherine E., Kamal, Sepehr, Johnson, James D., Gilmer, John, Long, Aideen, Kelleher, Dermot, Duggan, Shane P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408447/
https://www.ncbi.nlm.nih.gov/pubmed/32416156
http://dx.doi.org/10.1016/j.jcmgh.2020.05.002