Tousled-Like Kinases Suppress Innate Immune Signaling Triggered by Alternative Lengthening of Telomeres

The Tousled-like kinases 1 and 2 (TLK1/2) control histone deposition through the ASF1 histone chaperone and influence cell cycle progression and genome maintenance, yet the mechanisms underlying TLK-mediated genome stability remain uncertain. Here, we show that TLK loss results in severe chromatin d...

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Detalles Bibliográficos
Autores principales: Segura-Bayona, Sandra, Villamor-Payà, Marina, Attolini, Camille Stephan-Otto, Koenig, Lars M., Sanchiz-Calvo, Maria, Boulton, Simon J., Stracker, Travis H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408502/
https://www.ncbi.nlm.nih.gov/pubmed/32755577
http://dx.doi.org/10.1016/j.celrep.2020.107983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408502/
https://www.ncbi.nlm.nih.gov/pubmed/32755577
http://dx.doi.org/10.1016/j.celrep.2020.107983

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