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Improvement in the Oral Bioavailability and Efficacy of New Ezetimibe Formulations—Comparative Study of a Solid Dispersion and Different Micellar Systems

Ezetimibe (EZ) is a poorly water-soluble drug with low bioavailability. Strategies such as solid dispersions (SD) and micellar systems (MS) were developed to identify the most effective drug delivery formulations with the highest oral bioavailability, and to improve their lipid-lowering effect. The...

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Detalles Bibliográficos
Autores principales: Torrado-Salmerón, Carlos, Guarnizo-Herrero, Víctor, Gallego-Arranz, Teresa, del Val-Sabugo, Yvonne, Torrado, Guillermo, Morales, Javier, Torrado-Santiago, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408513/
https://www.ncbi.nlm.nih.gov/pubmed/32630626
http://dx.doi.org/10.3390/pharmaceutics12070617