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Improvement in the Oral Bioavailability and Efficacy of New Ezetimibe Formulations—Comparative Study of a Solid Dispersion and Different Micellar Systems
Ezetimibe (EZ) is a poorly water-soluble drug with low bioavailability. Strategies such as solid dispersions (SD) and micellar systems (MS) were developed to identify the most effective drug delivery formulations with the highest oral bioavailability, and to improve their lipid-lowering effect. The...
Autores principales: | Torrado-Salmerón, Carlos, Guarnizo-Herrero, Víctor, Gallego-Arranz, Teresa, del Val-Sabugo, Yvonne, Torrado, Guillermo, Morales, Javier, Torrado-Santiago, Santiago |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408513/ https://www.ncbi.nlm.nih.gov/pubmed/32630626 http://dx.doi.org/10.3390/pharmaceutics12070617 |
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