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The Constitutive Lack of α7 Nicotinic Receptor Leads to Metabolic Disorders in Mouse

Objective: Type 2 diabetes (T2D) occurs by deterioration in pancreatic β-cell function and/or progressive loss of pancreatic β-cell mass under the context of insulin resistance. α7 nicotinic acetylcholine receptor (nAChR) may contribute to insulin sensitivity but its role in the pathogenesis of T2D...

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Detalles Bibliográficos
Autores principales: Gausserès, Blandine, Liu, Junjun, Foppen, Ewout, Tourrel-Cuzin, Cécile, Rodriguez Sanchez-Archidona, Ana, Delangre, Etienne, Cruciani-Guglielmacci, Céline, Pons, Stéphanie, Maskos, Uwe, Thorens, Bernard, Magnan, Christophe, Movassat, Jamileh, Maouche, Kamel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408520/
https://www.ncbi.nlm.nih.gov/pubmed/32708537
http://dx.doi.org/10.3390/biom10071057