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The Long-Acting D3 Partial Agonist MC-25-41 Attenuates Motivation for Cocaine in Sprague-Dawley Rats

The dopamine D3 receptor is a prime target for developing treatments for cocaine use disorders (CUDs). In this study, we conducted a pre-clinical investigation of the therapeutic potential of a long-acting, D3 receptor partial agonist, MC-25-41. Male rats were pre-treated with MC-25-41 (vehicle, 1.0...

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Detalles Bibliográficos
Autores principales: Powell, Gregory L., Namba, Mark D., Vannan, Annika, Bonadonna, John Paul, Carlson, Andrew, Mendoza, Rachel, Chen, Peng-Jen, Luetdke, Robert R., Blass, Benjamin E., Neisewander, Janet L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408535/
https://www.ncbi.nlm.nih.gov/pubmed/32708461
http://dx.doi.org/10.3390/biom10071076