Bivalent Inhibitor with Selectivity for Trimeric MMP-9 Amplifies Neutrophil Chemotaxis and Enables Functional Studies on MMP-9 Proteoforms

A fundamental part of the immune response to infection or injury is leukocyte migration. Matrix metalloproteinases (MMPs) are a class of secreted or cell-bound endopeptidases, implicated in every step of the process of inflammatory cell migration. Hence, specific inhibition of MMPs is an interesting...

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Detalles Bibliográficos
Autores principales: Nuti, Elisa, Rossello, Armando, Cuffaro, Doretta, Camodeca, Caterina, Van Bael, Jens, van der Maat, Dries, Martens, Erik, Fiten, Pierre, Pereira, Rafaela Vaz Sousa, Ugarte-Berzal, Estefania, Gouwy, Mieke, Opdenakker, Ghislain, Vandooren, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408547/
https://www.ncbi.nlm.nih.gov/pubmed/32645949
http://dx.doi.org/10.3390/cells9071634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408547/
https://www.ncbi.nlm.nih.gov/pubmed/32645949
http://dx.doi.org/10.3390/cells9071634

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