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Ophthalmic In Situ Gelling System Containing Lanosterol Nanoparticles Delays Collapse of Lens Structure in Shumiya Cataract Rats

We attempted to prepare ophthalmic in situ gel formulations containing lanosterol (Lan) nanoparticles (LA-NPs/ISG) and investigated the characteristics, delivery pathway into the lens, and anti-cataract effects of LA-NPs/ISG using SCR-N (rats with slight lens structure collapse) and SCR-C (rats with...

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Detalles Bibliográficos
Autores principales: Nagai, Noriaki, Umachi, Kazuki, Otake, Hiroko, Oka, Mikako, Hiramatsu, Noriko, Sasaki, Hiroshi, Yamamoto, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408553/
https://www.ncbi.nlm.nih.gov/pubmed/32635523
http://dx.doi.org/10.3390/pharmaceutics12070629