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Mapping of Recognition Sites of Monoclonal Antibodies Responsible for the Inhibition of Pneumolysin Functional Activity

The pathogenicity of many bacteria, including Streptococcus pneumoniae, depends on pore-forming toxins (PFTs) that cause host cell lysis by forming large pores in cholesterol-containing cell membranes. Therefore, PFTs-neutralising antibodies may provide useful tools for reducing S. pneumoniae pathog...

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Detalles Bibliográficos
Autores principales: Kucinskaite-Kodze, Indre, Simanavicius, Martynas, Dapkunas, Justas, Pleckaityte, Milda, Zvirbliene, Aurelija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408604/
https://www.ncbi.nlm.nih.gov/pubmed/32650398
http://dx.doi.org/10.3390/biom10071009