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Potential Metabolite Nymphayol Isolated from Water Lily (Nymphaea stellata) Flower Inhibits MCF-7 Human Breast Cancer Cell Growth via Upregulation of Cdkn2a, pRb2, p53 and Downregulation of PCNA mRNA Expressions

Controlled production of cyclin dependent kinases (CDK) and stabilization of tumor suppressor genes are the most important factors involved in preventing carcinogenesis. The present study aimed to explore the cyclin dependent apoptotic effect of nymphayol on breast cancer MCF-7 cells. In our previou...

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Detalles Bibliográficos
Autores principales: Al-Harbi, Laila Naif, Subash-Babu, Pandurangan, Binobead, Manal Abdulaziz, Alhussain, Maha Hussain, AlSedairy, Sahar Abdulaziz, Aloud, Amal A, Alshatwi, Ali A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408605/
https://www.ncbi.nlm.nih.gov/pubmed/32650545
http://dx.doi.org/10.3390/metabo10070280