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Potential Metabolite Nymphayol Isolated from Water Lily (Nymphaea stellata) Flower Inhibits MCF-7 Human Breast Cancer Cell Growth via Upregulation of Cdkn2a, pRb2, p53 and Downregulation of PCNA mRNA Expressions
Controlled production of cyclin dependent kinases (CDK) and stabilization of tumor suppressor genes are the most important factors involved in preventing carcinogenesis. The present study aimed to explore the cyclin dependent apoptotic effect of nymphayol on breast cancer MCF-7 cells. In our previou...
Autores principales: | Al-Harbi, Laila Naif, Subash-Babu, Pandurangan, Binobead, Manal Abdulaziz, Alhussain, Maha Hussain, AlSedairy, Sahar Abdulaziz, Aloud, Amal A, Alshatwi, Ali A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408605/ https://www.ncbi.nlm.nih.gov/pubmed/32650545 http://dx.doi.org/10.3390/metabo10070280 |
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