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Soluble St2 Induces Cardiac Fibroblast Activation and Collagen Synthesis via Neuropilin-1

Circulating levels of soluble interleukin 1 receptor-like 1 (sST2) are increased in heart failure and associated with poor outcome, likely because of the activation of inflammation and fibrosis. We investigated the pathogenic role of sST2 as an inductor of cardiac fibroblasts activation and collagen...

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Detalles Bibliográficos
Autores principales: Matilla, Lara, Arrieta, Vanessa, Jover, Eva, Garcia-Peña, Amaia, Martinez-Martinez, Ernesto, Sadaba, Rafael, Alvarez, Virginia, Navarro, Adela, Fernandez-Celis, Amaya, Gainza, Alicia, Santamaria, Enrique, Fernandez-Irigoyen, Joaquín, Rossignol, Patrick, Zannad, Faiez, Lopez-Andres, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408622/
https://www.ncbi.nlm.nih.gov/pubmed/32664340
http://dx.doi.org/10.3390/cells9071667