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Identification of 5-Fluoro-5-Deoxy-Ribulose as a Shunt Fluorometabolite in Streptomyces sp. MA37

A fluorometabolite, 5-fluoro-5-deoxy-D-ribulose (5-FDRul), from the culture broth of the soil bacterium Streptomyces sp. MA37, was identified through a combination of genetic manipulation, chemo-enzymatic synthesis and NMR comparison. Although 5-FDRul has been chemically synthesized before, it was n...

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Detalles Bibliográficos
Autores principales: Wu, Linrui, Tong, Ming Him, Kyeremeh, Kwaku, Deng, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408626/
https://www.ncbi.nlm.nih.gov/pubmed/32664266
http://dx.doi.org/10.3390/biom10071023