DrugSniper, a Tool to Exploit Loss-Of-Function Screens, Identifies CREBBP as a Predictive Biomarker of VOLASERTIB in Small Cell Lung Carcinoma (SCLC)

The development of predictive biomarkers of response to targeted therapies is an unmet clinical need for many antitumoral agents. Recent genome-wide loss-of-function screens, such as RNA interference (RNAi) and CRISPR-Cas9 libraries, are an unprecedented resource to identify novel drug targets, repo...

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Detalles Bibliográficos
Autores principales: Carazo, Fernando, Bértolo, Cristina, Castilla, Carlos, Cendoya, Xabier, Campuzano, Lucía, Serrano, Diego, Gimeno, Marian, Planes, Francisco J., Pio, Ruben, Montuenga, Luis M., Rubio, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408696/
https://www.ncbi.nlm.nih.gov/pubmed/32645997
http://dx.doi.org/10.3390/cancers12071824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408696/
https://www.ncbi.nlm.nih.gov/pubmed/32645997
http://dx.doi.org/10.3390/cancers12071824

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