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Blockade of Platelet-Derived Growth Factor Signaling Inhibits Choroidal Neovascularization and Subretinal Fibrosis in Mice

Neovascular age related macular degeneration (nAMD) leads to severe vision loss worldwide and is characterized by the formation of choroidal neovascularization (CNV) and fibrosis. In the current study, we aimed to investigate the effect of blockade for platelet derived growth factor receptor-β (PDGF...

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Detalles Bibliográficos
Autores principales: Liu, Ye, Noda, Kousuke, Murata, Miyuki, Wu, Di, Kanda, Atsuhiro, Ishida, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408710/
https://www.ncbi.nlm.nih.gov/pubmed/32679740
http://dx.doi.org/10.3390/jcm9072242