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Nicotinamide nucleotide transhydrogenase (NNT) regulates mitochondrial ROS and endothelial dysfunction in response to angiotensin II

Endothelial dysfunction is a critical, initiating step in the development of hypertension (HTN) and mitochondrial reactive oxygen species (ROS) are important contributors to endothelial dysfunction. Genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) in the...

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Detalles Bibliográficos
Autores principales: Rao, K.N. Shashanka, Shen, Xinggui, Pardue, Sibile, Krzywanski, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408723/
https://www.ncbi.nlm.nih.gov/pubmed/32763515
http://dx.doi.org/10.1016/j.redox.2020.101650