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Mambalgin-2 Induces Cell Cycle Arrest and Apoptosis in Glioma Cells via Interaction with ASIC1a

Gliomas are fast growing and highly invasive brain tumors, characterized by tumor microenvironment acidification that drives glioma cell growth and migration. Channels containing Acid-sensing Ion Channel 1a subunit (ASIC1a) mediate amiloride-sensitive cation influx in late stage glioma cells, but no...

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Detalles Bibliográficos
Autores principales: Bychkov, Maxim, Shulepko, Mikhail, Osmakov, Dmitry, Andreev, Yaroslav, Sudarikova, Anastasia, Vasileva, Valeria, Pavlyukov, Marat S., Latyshev, Yaroslav A., Potapov, Alexander A., Kirpichnikov, Mikhail, Shenkarev, Zakhar O., Lyukmanova, Ekaterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408772/
https://www.ncbi.nlm.nih.gov/pubmed/32650495
http://dx.doi.org/10.3390/cancers12071837