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Advancements in PARP1 Targeted Nuclear Imaging and Theranostic Probes

The central paradigm of novel therapeutic approaches in cancer therapy is identifying and targeting molecular biomarkers. One such target is the nuclear DNA repair enzyme Poly-(ADP ribose) polymerase 1 (PARP1). Sensitivity to PARP inhibition in certain cancers such as gBRCA(mut) breast and ovarian c...

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Detalles Bibliográficos
Autores principales: Ambur Sankaranarayanan, Ramya, Kossatz, Susanne, Weber, Wolfgang, Beheshti, Mohsen, Morgenroth, Agnieszka, Mottaghy, Felix M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408801/
https://www.ncbi.nlm.nih.gov/pubmed/32640708
http://dx.doi.org/10.3390/jcm9072130