Glutamic-Pyruvic Transaminase 1 Facilitates Alternative Fuels for Hepatocellular Carcinoma Growth—A Small Molecule Inhibitor, Berberine

Metabolic reprogramming is an essential hallmark of cancer. Besides the “Warburg effect”, cancer cells also actively reprogram amino acid metabolism to satisfy high nutritional demands in a nutrient-poor environment. In the glucose–alanine cycle, exogenous alanine taken up by hepatocytes is converte...

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Detalles Bibliográficos
Autores principales: Guo, Wei, Tan, Hor-Yue, Li, Sha, Wang, Ning, Feng, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408817/
https://www.ncbi.nlm.nih.gov/pubmed/32660149
http://dx.doi.org/10.3390/cancers12071854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408817/
https://www.ncbi.nlm.nih.gov/pubmed/32660149
http://dx.doi.org/10.3390/cancers12071854

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