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HLA Evolutionary Divergence as a Prognostic Marker for AML Patients Undergoing Allogeneic Stem Cell Transplantation

The diversity of human leukocyte antigens (HLAs) enables the presentation of immense repertoires of peptides, including tumor-associated antigens (TAAs). As a surrogate for immunopeptidome diversity, the HLA evolutionary divergence (HED) between individual HLA alleles might directly define the abili...

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Detalles Bibliográficos
Autores principales: Roerden, Malte, Nelde, Annika, Heitmann, Jonas S., Klein, Reinhild, Rammensee, Hans-Georg, Bethge, Wolfgang A., Walz, Juliane S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408841/
https://www.ncbi.nlm.nih.gov/pubmed/32650450
http://dx.doi.org/10.3390/cancers12071835