Mechanisms of Androgen Receptor Agonist- and Antagonist-Mediated Cellular Senescence in Prostate Cancer

The androgen receptor (AR) plays a leading role in the control of prostate cancer (PCa) growth. Interestingly, structurally different AR antagonists with distinct mechanisms of antagonism induce cell senescence, a mechanism that inhibits cell cycle progression, and thus seems to be a key cellular re...

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Detalles Bibliográficos
Autores principales: Kokal, Miriam, Mirzakhani, Kimia, Pungsrinont, Thanakorn, Baniahmad, Aria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408918/
https://www.ncbi.nlm.nih.gov/pubmed/32650419
http://dx.doi.org/10.3390/cancers12071833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408918/
https://www.ncbi.nlm.nih.gov/pubmed/32650419
http://dx.doi.org/10.3390/cancers12071833

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