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Tacrolimus Prevents TWEAK-Induced PLA2R Expression in Cultured Human Podocytes

Primary membranous nephropathy is usually caused by antibodies against the podocyte antigen membrane M-type phospholipase A2 receptor (PLA2R). The treatment of membranous nephropathy is not fully satisfactory. The calcineurin inhibitor tacrolimus is used to treat membranous nephropathy, but recurren...

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Detalles Bibliográficos
Autores principales: Cuarental, Leticia, Valiño-Rivas, Lara, Mendonça, Luis, Saleem, Moin, Mezzano, Sergio, Sanz, Ana Belen, Ortiz, Alberto, Sanchez-Niño, Maria Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408934/
https://www.ncbi.nlm.nih.gov/pubmed/32664235
http://dx.doi.org/10.3390/jcm9072178