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Leucine-Rich Diet Modulates the Metabolomic and Proteomic Profile of Skeletal Muscle during Cancer Cachexia

Background: Cancer-cachexia induces a variety of metabolic disorders, including skeletal muscle imbalance. Alternative therapy, as nutritional supplementation with leucine, shows a modulatory effect over tumour damage in vivo and in vitro. Method: Adult rats distributed into Control (C), Walker tumo...

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Detalles Bibliográficos
Autores principales: Cruz, Bread, Oliveira, André, Viana, Lais Rosa, Lopes-Aguiar, Leisa, Canevarolo, Rafael, Colombera, Maiara Caroline, Valentim, Rafael Rossi, Garcia-Fóssa, Fernanda, de Sousa, Lizandra Maia, Castelucci, Bianca Gazieri, Consonni, Sílvio Roberto, Martins-de-Souza, Daniel, de Jesus, Marcelo Bispo, Russell, Steven Thomas, Gomes-Mardondes, Maria Cristina Cintra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408981/
https://www.ncbi.nlm.nih.gov/pubmed/32668598
http://dx.doi.org/10.3390/cancers12071880