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SNAIL Promotes Metastatic Behavior of Rhabdomyosarcoma by Increasing EZRIN and AKT Expression and Regulating MicroRNA Networks

Rhabdomyosarcoma (RMS) is a predominant soft tissue tumor in children and adolescents. For high-grade RMS with metastatic involvement, the 3-year overall survival rate is only 25 to 30%. Thus, understanding the regulatory mechanisms involved in promoting the metastasis of RMS is important. Here, we...

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Detalles Bibliográficos
Autores principales: Skrzypek, Klaudia, Kot, Marta, Konieczny, Paweł, Nieszporek, Artur, Kusienicka, Anna, Lasota, Małgorzata, Bobela, Wojciech, Jankowska, Urszula, Kędracka-Krok, Sylwia, Majka, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408994/
https://www.ncbi.nlm.nih.gov/pubmed/32664538
http://dx.doi.org/10.3390/cancers12071870