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The Biological Function of Sigma-2 Receptor/TMEM97 and Its Utility in PET Imaging Studies in Cancer
The sigma-2 receptor was originally defined pharmacologically and recently identified as TMEM97. TMEM97 has been validated as a biomarker of proliferative status and the radioligand of TMEM97, [(18)F]ISO-1, has been developed and validated as a PET imaging biomarker of proliferative status of tumors...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409002/ https://www.ncbi.nlm.nih.gov/pubmed/32668577 http://dx.doi.org/10.3390/cancers12071877 |