Identification of a Clinical Cutoff Value for Multiplex KRAS(G12/G13) Mutation Detection in Colorectal Adenocarcinoma Patients Using Digital Droplet PCR, and Comparison with Sanger Sequencing and PNA Clamping Assay

KRAS (Kirsten rat sarcoma 2 viral oncogene homolog) is a major predictive marker for anti-epidermal growth factor receptor treatment, and determination of KRAS mutational status is crucial for successful management of colorectal adenocarcinoma. More standardized and accurate methods for testing KRAS...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Kyung Ha, Lee, Tae Hee, Choi, Min Kyung, Kwon, In Sun, Bae, Go Eun, Yeo, Min-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409004/
https://www.ncbi.nlm.nih.gov/pubmed/32708359
http://dx.doi.org/10.3390/jcm9072283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409004/
https://www.ncbi.nlm.nih.gov/pubmed/32708359
http://dx.doi.org/10.3390/jcm9072283

Ejemplares similares