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Characterization of mTOR Activity and Metabolic Profile in Pediatric Rhabdomyosarcoma

mTOR activation has been observed in rhabdomyosarcoma (RMS); however, mTOR complex (mTORC) 1 inhibition has had limited success thus far. mTOR activation alters the metabolic pathways, which is linked to survival and metastasis. These pathways have not been thoroughly analyzed in RMSs. We performed...

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Detalles Bibliográficos
Autores principales: Felkai, Luca, Krencz, Ildikó, Kiss, Dorottya Judit, Nagy, Noémi, Petővári, Gábor, Dankó, Titanilla, Micsík, Tamás, Khoor, András, Tornóczky, Tamás, Sápi, Zoltán, Sebestyén, Anna, Csóka, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409076/
https://www.ncbi.nlm.nih.gov/pubmed/32709151
http://dx.doi.org/10.3390/cancers12071947