Adenoviral Vectors Armed with PAPILLOMAVIRUs Oncogene Specific CRISPR/Cas9 Kill Human-Papillomavirus-Induced Cervical Cancer Cells

Human papillomaviruses (HPV) cause malignant epithelial cancers including cervical carcinoma, non-melanoma skin and head and neck cancer. They drive tumor development through the expression of their oncoproteins E6 and E7. Designer nucleases were shown to be efficient to specifically destroy HPV16 a...

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Detalles Bibliográficos
Autores principales: Ehrke-Schulz, Eric, Heinemann, Sonja, Schulte, Lukas, Schiwon, Maren, Ehrhardt, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409089/
https://www.ncbi.nlm.nih.gov/pubmed/32708897
http://dx.doi.org/10.3390/cancers12071934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409089/
https://www.ncbi.nlm.nih.gov/pubmed/32708897
http://dx.doi.org/10.3390/cancers12071934

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