Characterisation of Ovarian Cancer Cell Line NIH-OVCAR3 and Implications of Genomic, Transcriptomic, Proteomic and Functional DNA Damage Response Biomarkers for Therapeutic Targeting

In order to be effective models to identify biomarkers of chemotherapy response, cancer cell lines require thorough characterization. In this study, we characterised the widely used high grade serous ovarian cancer (HGSOC) cell line NIH-OVCAR3 using bioinformatics, cytotoxicity assays and molecular/...

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Detalles Bibliográficos
Autores principales: Bradbury, Alice, O’Donnell, Rachel, Drew, Yvette, Curtin, Nicola J., Sharma Saha, Sweta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409137/
https://www.ncbi.nlm.nih.gov/pubmed/32709004
http://dx.doi.org/10.3390/cancers12071939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409137/
https://www.ncbi.nlm.nih.gov/pubmed/32709004
http://dx.doi.org/10.3390/cancers12071939

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