New CXCR4 Antagonist Peptide R (Pep R) Improves Standard Therapy in Colorectal Cancer

The chemokine receptor CXCR4 is overexpressed and functional in colorectal cancer. To investigate the role of CXCR4 antagonism in potentiating colon cancer standard therapy, the new peptide CXCR4 antagonist Peptide R (Pep R) was employed. Human colon cancer HCT116 xenograft-bearing mice were treated...

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Detalles Bibliográficos
Autores principales: D’Alterio, Crescenzo, Zannetti, Antonella, Trotta, Anna Maria, Ieranò, Caterina, Napolitano, Maria, Rea, Giuseppina, Greco, Adelaide, Maiolino, Piera, Albanese, Sandra, Scognamiglio, Giosuè, Tatangelo, Fabiana, Tafuto, Salvatore, Portella, Luigi, Santagata, Sara, Nasti, Guglielmo, Ottaiano, Alessandro, Pacelli, Roberto, Delrio, Paolo, Botti, Gerardo, Scala, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409147/
https://www.ncbi.nlm.nih.gov/pubmed/32708431
http://dx.doi.org/10.3390/cancers12071952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409147/
https://www.ncbi.nlm.nih.gov/pubmed/32708431
http://dx.doi.org/10.3390/cancers12071952

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