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Role of Telomeres and Telomeric Proteins in Human Malignancies and Their Therapeutic Potential
Telomeres are the ends of linear chromosomes comprised of repetitive nucleotide sequences in humans. Telomeres preserve chromosomal stability and genomic integrity. Telomere length shortens with every cell division in somatic cells, eventually resulting in replicative senescence once telomere length...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409176/ https://www.ncbi.nlm.nih.gov/pubmed/32674474 http://dx.doi.org/10.3390/cancers12071901 |