Cargando…
Role of Telomeres and Telomeric Proteins in Human Malignancies and Their Therapeutic Potential
Telomeres are the ends of linear chromosomes comprised of repetitive nucleotide sequences in humans. Telomeres preserve chromosomal stability and genomic integrity. Telomere length shortens with every cell division in somatic cells, eventually resulting in replicative senescence once telomere length...
Autores principales: | Fernandes, Stina George, Dsouza, Rebecca, Pandya, Gouri, Kirtonia, Anuradha, Tergaonkar, Vinay, Lee, Sook Y., Garg, Manoj, Khattar, Ekta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409176/ https://www.ncbi.nlm.nih.gov/pubmed/32674474 http://dx.doi.org/10.3390/cancers12071901 |
Ejemplares similares
-
Transcriptional Regulation of Telomerase Reverse Transcriptase (TERT) by MYC
por: Khattar, Ekta, et al.
Publicado: (2017) -
Non-canonical roles of canonical telomere binding proteins in cancers
por: Akincilar, Semih Can, et al.
Publicado: (2021) -
Telomerase inhibitor MST-312 and quercetin synergistically inhibit cancer cell proliferation by promoting DNA damage
por: Fernandes, Stina George, et al.
Publicado: (2022) -
Detection of alternative lengthening of telomeres by telomere quantitative PCR
por: Lau, Loretta M. S., et al.
Publicado: (2013) -
Telomere and Telomerase Therapeutics in Cancer
por: Xu, Yucheng, et al.
Publicado: (2016)