PVR and ICAM-1 on Blast Crisis CML Stem and Progenitor Cells with TKI Resistance Confer Susceptibility to NK Cells

The BCR-ABL1 fusion gene generating an oncogenic tyrosine kinase is a hallmark of chronic myeloid leukemia (CML), which can be successfully targeted by BCR-ABL1 tyrosine kinase inhibitors (TKIs). However, treatment-free remission has been achieved in a minority of patients due to evolving TKI resist...

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Detalles Bibliográficos
Autores principales: Kim, Nayoung, Kim, Mi-Yeon, Cho, Young-Uk, Chen, WenYong, Lee, Kyoo-Hyung, Kim, Hun Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409178/
https://www.ncbi.nlm.nih.gov/pubmed/32708713
http://dx.doi.org/10.3390/cancers12071923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409178/
https://www.ncbi.nlm.nih.gov/pubmed/32708713
http://dx.doi.org/10.3390/cancers12071923

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