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Genetic and Molecular Basis of Heterogeneous NK Cell Responses against Acute Leukemia

Natural killer (NK) cells are key cytotoxic effectors against malignant cells. Polygenic and polymorphic Killer cell Immunoglobulin-like Receptor (KIR) and HLA genes participate in the structural and functional formation of the NK cell repertoire. In this study, we extensively investigated the anti-...

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Detalles Bibliográficos
Autores principales: Makanga, Dhon Roméo, Da Rin de Lorenzo, Francesca, David, Gaëlle, Willem, Catherine, Dubreuil, Léa, Legrand, Nolwenn, Guillaume, Thierry, Peterlin, Pierre, Lebourgeois, Amandine, Béné, Marie Christine, Garnier, Alice, Chevallier, Patrice, Gendzekhadze, Ketevan, Cesbron, Anne, Gagne, Katia, Clemenceau, Béatrice, Retière, Christelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409189/
https://www.ncbi.nlm.nih.gov/pubmed/32708751
http://dx.doi.org/10.3390/cancers12071927