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Pre-Treatment Mutational and Transcriptomic Landscape of Responding Metastatic Melanoma Patients to Anti-PD1 Immunotherapy

Immunotherapy, such as anti-PD1, has improved the survival of patients with metastatic melanoma. However, predicting which patients will respond to immunotherapy remains a significant knowledge gap. In this study we analyzed pre-immunotherapy treated tumors from 52 patients with metastatic melanoma...

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Detalles Bibliográficos
Autores principales: Amato, Carol M., Hintzsche, Jennifer D., Wells, Keith, Applegate, Allison, Gorden, Nicholas T., Vorwald, Victoria M., Tobin, Richard P., Nassar, Kelsey, Shellman, Yiqun G., Kim, Jihye, Medina, Theresa M., Rioth, Matthew, Lewis, Karl D., McCarter, Martin D., Gonzalez, Rene, Tan, Aik-Choon, Robinson, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409244/
https://www.ncbi.nlm.nih.gov/pubmed/32708981
http://dx.doi.org/10.3390/cancers12071943