Cargando…

CUX1—Transcriptional Master Regulator of Tumor Progression in Pancreatic Neuroendocrine Tumors

Recently, we identified the homeodomain transcription factor Cut homeobox 1 (CUX1) as mediator of tumour de-differentiation and metastatic behaviour in human insulinoma patients. In insulinomas, CUX1 enhanced tumour progression by stimulating proliferation and angiogenesis in vitro and in vivo. In p...

Descripción completa

Detalles Bibliográficos
Autores principales: Krug, Sebastian, Weissbach, Julia, Blank, Annika, Perren, Aurel, Haybaeck, Johannes, Fendrich, Volker, Rinke, Anja, Gress, Thomas Mathias, Rosendahl, Jonas, Michl, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409270/
https://www.ncbi.nlm.nih.gov/pubmed/32707646
http://dx.doi.org/10.3390/cancers12071957