Characterization of Driver Mutations in Anaplastic Thyroid Carcinoma Identifies RAS and PIK3CA Mutations as Negative Survival Predictors

Anaplastic thyroid carcinoma (ATC) is rare but highly aggressive. We investigated the association of selected driver mutations, including BRAF, RAS, PIK3CA, TERT promoter, TP53, POLE, and mismatch repair deficiency (MMR-D) with the clinicopathological features of ATC to identify prognostic and predi...

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Detalles Bibliográficos
Autores principales: Lai, Wei-An, Liu, Chih-Yi, Lin, Shih-Yao, Chen, Chien-Chin, Hang, Jen-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409295/
https://www.ncbi.nlm.nih.gov/pubmed/32698386
http://dx.doi.org/10.3390/cancers12071973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409295/
https://www.ncbi.nlm.nih.gov/pubmed/32698386
http://dx.doi.org/10.3390/cancers12071973

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