Dual-Agent Photodynamic Therapy with Optical Clearing Eradicates Pigmented Melanoma in Preclinical Tumor Models

Treatment using light-activated photosensitizers (photodynamic therapy, PDT) has shown limited efficacy in pigmented melanoma, mainly due to the poor penetration of light in this tissue. Here, an optical clearing agent (OCA) was applied topically to a cutaneous melanoma model in mice shortly before...

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Detalles Bibliográficos
Autores principales: Pires, Layla, Demidov, Valentin, Wilson, Brian C., Salvio, Ana Gabriela, Moriyama, Lilian, Bagnato, Vanderlei S., Vitkin, I. Alex, Kurachi, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409296/
https://www.ncbi.nlm.nih.gov/pubmed/32708501
http://dx.doi.org/10.3390/cancers12071956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409296/
https://www.ncbi.nlm.nih.gov/pubmed/32708501
http://dx.doi.org/10.3390/cancers12071956

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