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Cancer Stem Cell-Inducing Media Activates Senescence Reprogramming in Fibroblasts

Cellular senescence is a tumor-suppressive mechanism blocking cell proliferation in response to stress. However, recent evidence suggests that senescent tumor cells can re-enter the cell cycle to become cancer stem cells, leading to relapse after cancer chemotherapy treatment. Understanding how the...

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Detalles Bibliográficos
Autores principales: Perrigue, Patrick M., Rakoczy, Magdalena, Pawlicka, Kamila P., Belter, Agnieszka, Giel-Pietraszuk, Małgorzata, Naskręt-Barciszewska, Mirosława, Barciszewski, Jan, Figlerowicz, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409320/
https://www.ncbi.nlm.nih.gov/pubmed/32629974
http://dx.doi.org/10.3390/cancers12071745