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Equine Alphaherpesviruses Require Activation of the Small GTPases Rac1 and Cdc42 for Intracellular Transport

Viruses utilize host cell signaling to facilitate productive infection. Equine herpesvirus type 1 (EHV-1) has been shown to activate Ca2+ release and phospholipase C upon contact with α4β1 integrins on the cell surface. Signaling molecules, including small GTPases, have been shown to be activated do...

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Detalles Bibliográficos
Autores principales: Kolyvushko, Oleksandr, Kelch, Maximilian A., Osterrieder, Nikolaus, Azab, Walid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409331/
https://www.ncbi.nlm.nih.gov/pubmed/32645930
http://dx.doi.org/10.3390/microorganisms8071013