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EpCAM-Binding DARPins for Targeted Photodynamic Therapy of Ovarian Cancer

Ovarian cancer is the most lethal gynecological malignancy due to late detection associated with dissemination throughout the abdominal cavity. Targeted photodynamic therapy (tPDT) aimed at epithelial cell adhesion molecule (EpCAM), overexpressed in over 90% of ovarian cancer metastatic lesions, is...

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Detalles Bibliográficos
Autores principales: van den Brand, Dirk, van Lith, Sanne A. M., de Jong, Jelske M., Gorris, Mark A. J., Palacio-Castañeda, Valentina, Couwenbergh, Stijn T., Goldman, Mark R. G., Ebisch, Inge, Massuger, Leon F., Leenders, William P. J., Brock, Roland, Verdurmen, Wouter P. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409335/
https://www.ncbi.nlm.nih.gov/pubmed/32630661
http://dx.doi.org/10.3390/cancers12071762