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EpCAM-Binding DARPins for Targeted Photodynamic Therapy of Ovarian Cancer
Ovarian cancer is the most lethal gynecological malignancy due to late detection associated with dissemination throughout the abdominal cavity. Targeted photodynamic therapy (tPDT) aimed at epithelial cell adhesion molecule (EpCAM), overexpressed in over 90% of ovarian cancer metastatic lesions, is...
Autores principales: | van den Brand, Dirk, van Lith, Sanne A. M., de Jong, Jelske M., Gorris, Mark A. J., Palacio-Castañeda, Valentina, Couwenbergh, Stijn T., Goldman, Mark R. G., Ebisch, Inge, Massuger, Leon F., Leenders, William P. J., Brock, Roland, Verdurmen, Wouter P. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409335/ https://www.ncbi.nlm.nih.gov/pubmed/32630661 http://dx.doi.org/10.3390/cancers12071762 |
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