Mitochondrial spongiotic brain disease: astrocytic stress and harmful rapamycin and ketosis effect

Mitochondrial DNA (mtDNA) depletion syndrome (MDS) is a group of severe, tissue-specific diseases of childhood with unknown pathogenesis. Brain-specific MDS manifests as devastating spongiotic encephalopathy with no curative therapy. Here, we report cell type–specific stress responses and effects of...

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Detalles Bibliográficos
Autores principales: Ignatenko, Olesia, Nikkanen, Joni, Kononov, Alexander, Zamboni, Nicola, Ince-Dunn, Gulayse, Suomalainen, Anu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409372/
https://www.ncbi.nlm.nih.gov/pubmed/32737078
http://dx.doi.org/10.26508/lsa.202000797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409372/
https://www.ncbi.nlm.nih.gov/pubmed/32737078
http://dx.doi.org/10.26508/lsa.202000797

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